James A Tumlin Selected Research

Cyclosporine (Ciclosporin)

2/2007

Loss of the alpha-isoform of calcineurin is sufficient to induce nephrotoxicity and altered expression of transforming growth factor-beta.

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James A Tumlin Research Topics

Disease

11	Acute Kidney Injury (Acute Renal Failure) 01/2018 - 07/2005
10	Proteinuria 12/2023 - 07/2003
8	IGA Glomerulonephritis (IGA Nephropathy) 12/2023 - 07/2003
5	Renal Insufficiency (Renal Failure) 12/2023 - 07/2005
4	Cardiac Arrhythmias (Arrythmia) 04/2024 - 04/2016
3	Fibrosis (Cirrhosis) 01/2023 - 07/2003
3	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2018 - 01/2006
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 03/2011 - 02/2003
2	Anemia 01/2022 - 11/2018
2	Chronic Renal Insufficiency 01/2022 - 11/2003
2	Lupus Nephritis 08/2021 - 08/2008
2	Sudden Death 01/2019 - 04/2016
2	Inflammation (Inflammations) 11/2018 - 02/2007
2	Critical Illness (Critically Ill) 09/2013 - 01/2007
2	Hypotension (Low Blood Pressure) 02/2013 - 12/2009
2	Glomerulonephritis 03/2011 - 05/2004
2	Hypertension (High Blood Pressure) 09/2007 - 05/2004
2	Chronic Kidney Failure (Chronic Renal Failure) 09/2007 - 05/2004
1	Hematuria 01/2023
1	Heart Arrest (Cardiac Arrest) 11/2022
1	Bradycardia 11/2022
1	Atrial Fibrillation 02/2022
1	Hypoxia (Hypoxemia) 01/2022
1	Type 2 Diabetes Mellitus (MODY) 11/2018
1	Albuminuria 11/2018
1	Diabetic Nephropathies (Diabetic Nephropathy) 11/2018
1	Shock 01/2018
1	Coronary Artery Disease (Coronary Atherosclerosis) 09/2015
1	Neoplasms (Cancer) 09/2015
1	Diarrhea 02/2013
1	Hypophosphatemia 02/2013
1	Heart Failure 01/2013
1	Pulmonary Embolism 06/2012
1	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 03/2011
1	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 03/2011
1	Membranous Glomerulonephritis (Membranous Nephropathy) 03/2011
1	Nephrotic Syndrome (Syndrome, Nephrotic) 03/2011
1	Infections 03/2011
1	Ischemia 12/2009
1	Disease Progression 09/2007
1	Necrosis 07/2005

Drug/Important Bio-Agent (IBA)

10	CreatinineIBA 12/2023 - 07/2003
5	Fenoldopam (Corlopam)FDA LinkGeneric 12/2009 - 11/2003
3	Immunoglobulin A (IgA)IBA 03/2011 - 05/2004
3	SteroidsIBA 03/2011 - 07/2003
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 08/2008 - 07/2003
2	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2006
2	Angiotensin Receptor AntagonistsIBA 12/2023 - 04/2017
2	abetimusIBA 08/2008 - 02/2003
2	Calcineurin InhibitorsIBA 02/2007 - 01/2006
1	sparsentanIBA 12/2023
1	Endothelins (Endothelin)IBA 12/2023
1	Irbesartan FDA LinkGeneric 12/2023
1	LectinsIBA 01/2023
1	Erythropoietin FDA Link 01/2022
1	vadadustatIBA 01/2022
1	Darbepoetin alfa (Aranesp)FDA Link 01/2022
1	HematinicsIBA 01/2022
1	Hemoglobins (Hemoglobin)IBA 01/2022
1	IronIBA 01/2022
1	Prolyl-Hydroxylase InhibitorsIBA 01/2022
1	Complement C5 (Complement 5)IBA 08/2021
1	Pancreatic Elastase (Elastase)IBA 08/2021
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 08/2021
1	narsoplimabIBA 11/2020
1	CalciumIBA 01/2019
1	Dialysis SolutionsIBA 01/2019
1	insulin receptor-related receptor (IRR)IBA 01/2019
1	ElectrolytesIBA 01/2019
1	PotassiumIBA 01/2019
1	MagnesiumIBA 01/2019
1	Janus KinasesIBA 11/2018
1	baricitinibIBA 11/2018
1	Angiotensin IIIBA 01/2018
1	Rituximab (Mabthera)FDA Link 04/2017
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 04/2017
1	AntibodiesIBA 04/2017
1	Contrast MediaIBA 09/2015
1	Biomarkers (Surrogate Marker)IBA 02/2014
1	Furosemide (Lasix)FDA LinkGeneric 09/2013
1	Sevelamer (RenaGel)FDA Link 02/2013
1	AngiotensinogenIBA 02/2013
1	DiureticsIBA 01/2013
1	4- ((1,4,8,11- tetraazacyclotetradec- 1- yl)methyl)benzoic acidIBA 06/2012
1	Adrenocorticotropic Hormone (ACTH)FDA Link 03/2011
1	Vasodilator Agents (Vasodilators)IBA 12/2009
1	ProstaglandinsIBA 11/2009
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2008
1	anti-dsDNA autoantibodyIBA 08/2008
1	DNA (Deoxyribonucleic Acid)IBA 08/2008
1	Transforming Growth Factor beta (TGF-beta)IBA 02/2007
1	CalcineurinIBA 02/2007
1	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2007
1	Protein Isoforms (Isoforms)IBA 02/2007
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 02/2007
1	Sirolimus (Rapamycin)FDA Link 01/2006

Therapy/Procedure

8	Therapeutics 01/2023 - 07/2003
5	Renal Dialysis (Hemodialysis) 04/2024 - 04/2016
3	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2018 - 01/2007
1	Critical Care (Surgical Intensive Care) 01/2007